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Regulatory agencies such as the European Food Safety Authority (EFSA) and the U.S. Food and Drug Administration (FDA) have recognized pimaricin as a safe food additive when used within specified limits. Manufacturers must adhere to these regulations to ensure that products remain within the prescribed safety standards.

Beyond thickening, E1404 also acts as an emulsifier, helping to blend oil and water components in products like mayonnaise and salad dressings. This property is vital, as it improves the overall quality and appearance of the food. Additionally, E1404 can serve as a fat replacer in low-fat and reduced-calorie products, providing a creamy texture without the added calories.

Some vitamins that don't always get labeled with their corresponding letter are thiamin (B1) riboflavin (B2) niacin (B3) and folic acid (B9); the B vitamins, like others, are essential for normal body functions.

However, the sale of monosodium glutamate is not without its challenges. Despite being recognized by food safety authorities, including the FDA and WHO, MSG has faced scrutiny and skepticism due to concerns about its health effects. Some consumers report adverse reactions to MSG, including headaches and allergic symptoms, which has led to a negative perception among certain demographics. As a result, food manufacturers are increasingly exploring natural alternatives to MSG, such as yeast extract and natural flavorings, to cater to health-conscious consumers.